Whether you call me a pessimist or a realist, I am an advocate of having a large number of safety schools on your list when applying to medical school.
I have some clients with good GPAs and mediocre MCATs and vice versa. Ensure that your safety schools include those whose averages are the same and lower than your weakest numbers. In other words, if you have a strong MCAT but a weaker GPA, pick safety schools that reflect the GPA.
Remember: You can always decline a medical school's offer of admission; you do not want to be without options.